Anesthesia, consciousness and hydrophobic pockets -
a unitary quantum hypothesis of anesthetic action

by
Hameroff S.
Department of Anesthesiology,
The University of Arizona, Tucson, USA.
hameroff@u.arizona.edu
Toxicol Lett. 1998 Nov 23;100-101:31-9.


ABSTRACT

1. consensus view holds that anesthetics act by van der Waals forces in hydrophobic pockets of select brain proteins to ablate consciousness. 2. What is consciousness? Enigmatic features of consciousness (e.g. 'qualia', binding, non-computability, pre-conscious-->conscious transition, nondeterministic free will) may be explained by the occurrence of quantum coherent states in the brain. 3. Van der Waals electron pair couplings (London forces) in hydrophobic pockets in non-anesthetic (conscious) conditions are a particular type of quantum capable of supporting macroscopic quantum coherence. 4. The mechanism of anesthetics may be to inhibit electron mobility and London forces necessary for quantum states and consciousness in hydrophobic pockets of select brain proteins.
1846
People
Anaesthesia
Hypnotic analgesia
Obstetric anaesthesia
Molecular mechanisms
Chloroform anaesthesia
A thalamocortical switch?



Refs
and further reading

general-anaesthesia.com
HOME
HedWeb
Nootropics
Cocaine.org
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhappiness?
Utopian Surgery?
The Good Drug Guide
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World