The numbing effect of chewing coca leaves had long been known; but this action had long been disregarded as an unwanted side-effect. Dr Koller realised that cocaine was an ideal local anaesthetic for eye surgery, its only real drawback being that it is also an eminentlty abusable euphoriant.
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Karl Koller
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erythroxylum-coca.com
Utopian Surgery
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Anaesthesia and Anaesthetics